Casodex (Bicalutamide) – What You Need to Know
If you've been prescribed Casodex, you probably have a lot of questions. It's a brand name for the drug bicalutamide, used mainly in prostate cancer treatment. Basically, it blocks male hormones that can make the cancer grow. This guide breaks down how it works, how to take it, and what to watch out for.
How Casodex Works and When It's Used
Casodex is part of hormone‑blocking therapy. It stops testosterone from binding to cancer cells, which slows down tumor growth. Doctors usually give it with another hormone treatment called a GnRH agonist, but sometimes it's used alone if surgery isn’t an option. It's most common in men with advanced or metastatic prostate cancer.
Dosage, Timing, and Storage
The typical dose is 50 mg taken once a day, with or without food. Swallow the tablet whole—don’t crush or chew it. If you miss a dose, take it as soon as you remember, unless it’s almost time for the next one; then just skip the missed dose. Store Casodex at room temperature away from moisture and heat.
Keeping a regular schedule matters. Set a daily alarm or use a pill organizer so you don’t forget. If you’re traveling across time zones, talk to your doctor about how to adjust the timing.
Common Side Effects to Expect
Most men experience some side effects. The most frequent ones include hot flashes, breast tenderness or enlargement, and mild stomach upset. Some people notice reduced libido or erectile changes. These are usually manageable, but let your doctor know if they become severe.
Less common but more serious reactions can involve liver problems, severe skin rash, or allergic reactions. Signs of liver trouble include yellowing of the skin or eyes, dark urine, and persistent nausea. If any of these happen, seek medical help right away.
Tips for Managing Side Effects
Staying hydrated and avoiding alcohol can help with hot flashes and liver health. If breast tenderness bothers you, a supportive bra and warm (not hot) compresses can ease discomfort. For stomach upset, take Casodex with a small meal or snack.
Regular blood tests are key. Your doctor will likely check liver enzymes and hormone levels every few months. This lets them spot issues early and adjust the dose if needed.
When to Contact Your Doctor
Call your healthcare provider if you notice any new or worsening symptoms—especially yellow skin, severe rash, or breathing difficulties. Also, let them know if you start any new medications, including over‑the‑counter supplements, because they can interact with Casodex.
Never stop taking Casodex without talking to your doctor. Stopping abruptly can cause a sudden hormone surge, which may worsen the cancer.
Putting It All Together
Casodex is a powerful tool in the fight against prostate cancer, but like any medication, it works best when you understand how to use it safely. Follow the prescribed schedule, keep an eye on side effects, and stay in touch with your doctor for regular monitoring. By staying informed and proactive, you can make the most of your treatment and keep side effects in check.

Casodex (Bicalutamide) vs Other Prostate Cancer Drugs - A Detailed Comparison
Sep, 24 2025
Explore how Casodex (bicalutamide) compares with other androgen‑targeting drugs for prostate cancer, covering mechanism, efficacy, side‑effects and choosing the right option.
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