Alternatives to Symbicort: Real Options for Asthma & COPD Relief

If you’re on Symbicort but need a change—maybe because of side effects, insurance, or just curiosity—there are plenty of other inhalers that can keep your lungs happy. Below you’ll find the most common substitutes, how they differ, and what to think about before you switch.

Why you might need a different inhaler

Symbicort mixes a steroid (budesonide) with a long‑acting bronchodilator (formoterol). While that combo works for many, some people experience throat irritation, oral thrush, or trouble getting the right dose. Insurance plans can also push a higher co‑pay, making another brand more affordable. And if you’re using a device that’s hard to operate, a simpler inhaler might give you better control.

Top replacement inhalers you can consider

Advair (fluticasone/salmeterol) – This is the closest match to Symbicort. It combines the same steroid class with a different bronchodilator. Most people find the dosing schedule similar, but the inhaler design feels different, so give it a try if you struggle with the Symbicort mouthpiece.

Breo Ellipta (fluticasone furoate/vilanterol) – Breo offers once‑daily dosing, which can be a game‑changer for busy schedules. The Ellipta inhaler clicks into place, making it easy to tell if you’ve taken a dose. It’s a solid choice if you want fewer daily steps.

Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol) – Trelegy adds a third component, a long‑acting anticholinergic, to target both asthma and COPD symptoms. If you have mixed lung issues, this triple therapy can simplify your regimen to one puff a day.

AirFluS (fluticasone propionate) – A steroid‑only inhaler works well if you only need anti‑inflammatory control and your bronchodilator can be taken separately (like albuterol). Pairing it with a short‑acting rescue inhaler can give you flexibility without the combo.

Combivent Respimat (ipratropium/albuterol) – If you’re leaning toward a non‑steroid route, Combivent gives a short‑acting anticholinergic plus a quick‑relief bronchodilator. It’s not a direct Symbicort substitute but can manage flare‑ups when steroids aren’t an option.

Before you switch, talk to your doctor or pharmacist. They’ll check your lung function, review any allergies, and make sure the new inhaler matches your dosing needs. Also, ask about a proper wash‑out period—some doctors prefer a short break to avoid overlapping steroids.

When you get a new inhaler, practice the technique. Most devices have a “dose counter” and require you to shake or press a button before inhaling. A quick video demo from the manufacturer can save you from common mistakes like not breathing in deeply enough.

Finally, keep an eye on side effects. Any inhaled steroid can cause throat irritation, so rinsing your mouth after each use is a simple habit that cuts down on thrush. If you notice new symptoms, contact your healthcare provider promptly.

Switching from Symbicort doesn’t have to be stressful. With the right information, a few minutes of practice, and a check‑in with your clinician, you can find an inhaler that fits your lifestyle, budget, and health goals. Breathe easy—you’ve got options.